Bubble Trouble II: Rebubbled is a timed bubble-popping game. Across four modes (i.e., 1 Player, 2 Player, Staying Alive, and More Levels!), a pink devil wearing black sunglasses and a trench coat needs at least one player to help him pop bubbles.
In all modes, a player or players direct their devil to move left and right, shoot a handheld harpoon weapon at small, medium and large bouncing bubbles, and earn high scores. With 2 Player mode, each player tries to outperform their opponent. In the Staying Alive mode, the player tries to prevent the devil's death across 31 levels. Lastly, More Levels! challenges the player with varying levels of difficulty in user-created levels.
The player directs their devil character to clear a level by shooting all bubbles. They track their score in the lower-right area. The game provides them with penalty passes in the lower-left area that allow the character to die a limited number of times per level without a penalty.
On the Bubble Trouble 2: Rebubbled home screen, the player uses the Fresh button to claim XP for specific achievements, such as finishing the third level, popping a preset number of bubbles, and shooting the harpoon a specific number of times. A button marked with three up arrows allows them to perform upgrades and achieve new ranks.
The player can earn extra overall time, freeze time, bonus drop pickup time, a spiky shield to pop bubbles, and a bonus medal opportunity. They can collect bronze, silver, gold and diamond medals.